عرض تفاصيل البحث

ادناه جميع التفاصيل الخاصة بالبحث المطلوب عرضه. توفر هذه المنصة معلومات اساسية حول البحث, لمزيد من التفاصيل يرجى متابعة التصفح من خلال الضغط على الرابط الاصلي للبحث او رابط DOI.

عنوان البحث
Estimation Of Prognostic Factors For Non-Alcoholic Fatty Liver Disease Using The Liver Fat Score In Patients At Al-Rifai Teaching Hospital In The Al-Rifai District Of Dhi-Qar, Iraq
عنوان المجلة
World Journal Of Advance Healthcare Research
ISSN-2457-0400
تفاصيل النشر
سنة النشر - 2024 / الفهرس الاصلي للمجلة - 8 : 10 (عدد الصفحات 6)
تصنيف البحث
physiology - المجموعة الطبية
رابط DOI
https://www.wjahr.com/admin/assets/article_issue/65092024/1728038573.pdf
رابط البحث
فتح في موقع المجلة الرسمي
البحث والاستدامة
غير مرتبط باهداف التنمية المستدامة  
البحث والمجتمع
نعم , يدعم
الكلمات المفتاحية
Prognostic Factors, Non-Alcoholic, Fatty, Liver Disease, Liver Fat Score.

اسم الباحثجهة الانتساببلد الباحث
Auday Abdul Razaq Alhusseiny University of Sumer Iraq
Sadeq Lafta Mousa Alzamili University of Sumer Iraq
Hatim Abdul Kareem Jabur Alshwilly University of Sumer Iraq

Background: Non-alcoholic fatty liver disease (NAFLD) is a highly prevalent condition with varying severity. Non-invasive methods like liver function score (LFS) assist diagnosis but their accuracy across disease stages requires further evaluation. Objectives: To evaluate LFS sensitivity compared to ultrasound and analyze biochemical differences across steatosis grades and in discordant LFS/ultrasound results. Secondary aims were assessing correlations of LFS and biomarkers and influence of comorbidities on LFS accuracy. Methods: 71 adult NAFLD patients were recruited. Hepatic steatosis was graded by ultrasound as mild (U1), moderate (U2) or severe (U3). LFS, ferritin, mean platelet volume and neutrophil-to-lymphocyte ratio were measured. One-way ANOVA compared groups. Pearson’s coefficients evaluated correlations. Results: LFS demonstrated lower sensitivity for mild (63.63%) versus moderate (70.58%) and severe (100%) NAFLD. Total cholesterol, LDLcholesterol, AST, ALT and anemia markers significantly worsened with increasing ultrasound grade. No inflammatory biomarkers distinguished steatosis severity or LFS accuracy. High prevalence of metabolic comorbidities had no significant differences across grades. Conclusion: LFS showed adequate overall accuracy for NAFLD but substantially lower sensitivity for mild disease, highlighting complexity in early diagnosis. Worsening biochemical aberrations were associated with more advanced illness on imaging. The lack of reliable inflammatory indicators represents an area for further research.
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